Wednesday, February 11, 2015

Drug Interactions

I take many medications.  Medical professionals with different specialties prescribe medications for me.  Physicians in one specialty are rarely familiar enough with medications out of their specialty to know which drugs might cause interactions.  Therefore, it is up to you and your pharmacist to ensure your medications don't produce harmful drug interactions.

I've spent many weeks working with both a clinical pharmacologist and online research tools to figure out which drug interactions I must avoid.  I am not currently taking all of these drugs, instead this list represents the list of drugs I've researched because I have taken or thought I might take them in the future.

Some of these interactions are more dangerous than others.  If you have a condition similar to that described (e.g. congenital long QT interval + heart arrhythmia), then you should strongly consider avoiding that combination.

Do not stop taking your medications because of a drug interaction but do contact your physician and figure out alternative medications.

Standard Disclaimer: I am not a medical professional.  You should not base your treatment upon the following list.

With no further adieu, here's my list of drug interactions for the drugs I have taken, will take, or thought I might take.



Drug 1 Drug 2 Notes
Acetaminophen Norco / Vicodin Norco contains Acetaminophen keep daily dosage of Acetaminophen under 3000 mg
Aspirin Ciprofloxicin Rare tremors, seizures, hallucinations
Aspirin Ibuprofen Do not take together.
Aspirin Methotrexate Increases effects of methotrexate
Azathioprine Methotrexate Do not take together
Azathioprine Prednisone Increased risk of infection
Azathioprine Remicade Increased risk of infection
Azathioprine Sulfasalazine Increased risk of infection
Bentyl Levsin ER Do not take together.
Bentyl Loperamide HCl Amplifies Bentyl's and Imodium's effects
Bentyl Meclizine Can amplify effects
Centrum Multivitamin Ciprofloxicin Calcium in Centrum blocks the absorption of Ciprofloxicin
Ciprofloxicin Aspirin Rare tremors, seizures, hallucinations
Ciprofloxicin Centrum Multivitamin Calcium blocks absorption of Cipro
Ciprofloxicin Ibuprofen Rare tremors, seizures, hallucinations
Ciprofloxicin Norco / Vicodin Increases effects of hydrocodone
Diflucan Fish oil Blocks absorption of Diflucan
Diflucan Norco / Vicodin Increases effects of hydrocodone
Diflucan Omeprazole Potential heart arrhythmia
Diflucan Phenergan Potential heart arrhythmia
Diflucan Zofran Potential heart arrhythmia
Fish Oil Diflucan Fish oil blocks absorption of Diflucan
Flagyl Does not interact with my drugs
Floucinolone Acetonide Does not interact with my drugs
Ibuprofen Ciprofloxicin Rare tremors, seizures, hallucinations
Lansoprazole Fish oil Assume Lansoprazole blocks absorption of Fish oil
Lansoprazole Vitamin D Assume Lansoprazole blocks absorption Vit D
Levsin ER Bentyl Do not take together.
Levsin ER Loperamide HCl Can amplify effects
Levsin ER Meclizine Can amplify effects
Loperamide Bentyl Can amplify effects
Loperamide Levsin ER Can amplify effects
Loperamide Meclizine Can amplify effects
Meclizine Bentyl Can amplify effects
Meclizine Loperamide HCl Can amplify effects
Meclizine Levsin ER Can amplify effects
Melatonin Does not interact with my drugs
Methotrexate Acetaminophen Possible liver damage
Methotrexate Azathioprine Do not take together
Methotrexate Prednisone Increased risk of infection
Methotrexate Remicade Increased risk of infection
Methotrexate Sulfasalazine Increased risk of infection
Niacin Does not interact with my drugs
Norco Acetaminophen Norco contains Acetaminophen keep cumulative daily dosage of Acetaminophen under 3000 mg
Norco Ciprofloxicin Amplifies effects of hydrocodone
Norco Diflucan Amplifies effects of hydrocodone
Omeprazole Diflucan Can cause heart arrhythmia
Omeprazole Fish oil Blocks absorption of Fish Oil
Omeprazole Vitamin D Blocks absorption of Vitamin D
Phenergan Bentyl Amplifies effects of Bentyl & Phenergan
Phenergan Diflucan Can cause heart arrhythmia
Phenergan Loperamide HCl Amplifies anti-motility effects
Prednisone Azathioprine Increased risk of infection
Prednisone Methotrexate Increased risk of infection
Prednisone Remicade Increased risk of infection
Prednisone Sulfasalazine Increased risk of infection
Remicade Azathioprine Increased risk of infection
Remicade Methotrexate Increased risk of infection
Remicade Prednisone Increased risk of infection
Remicade Sulfasalazine Increased risk of infection
Sulfasalazine Azathioprine Increased risk of infection
Sulfasalazine Methotrexate Increased risk of infection
Sulfasalazine Prednisone Increased risk of infection
Sulfasalazine Remicade Increased risk of infection
Trilipix Does not interact with my drugs
Vitamin B-12 Does not interact with my drugs
Vitamin C Does not interact with my drugs
Vitamin D3 Diflucan Vitamin D blocks absorption of Diflucan
Vitamin D3 Lansoprazole Blocks absorption of Vitamin D
Vitamin D3 Omeprazole Blocks absorption of Vitamin D
Zofran Diflucan Can cause heart arrhythmia

If you want to check your drug interactions, I suggest using sites like Drugs.com to check for your specific drug interaction.

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